Optimized oxidoreductases for medium and large scale industrial biotransformations
Project Secretariat
Dr Marta Pérez-Boada
E-mail: MPBoada@cib.csic.es
Consejo Superior de Investigaciones Científicas (CSIC)
Biological Research Centre (CIB)
Calle Ramiro de Maeztu 9, E-28040 Madrid, Spain
Phone: 34 918373112
Fax: 34 915360432
Mobile: 34 650080476
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about us
inra Institut National de la Recherche Agronomique, Marseille, France (INRA)

Craig & Eric
Contact information
E. Record, INRA, UMR1163 Biotechnologie des Champignons Filamenteux, Aix -Marseille Université, Polytech Marseille, 163 avenue de Luminy, CP 925, 13288 Marseille Cedex 09, France

Phone: 33 491828607
Fax: 33 491828601
E-mail: eric.record@univ-amu.fr

Description of the group
Since its creation, the research group INRA BCF (http://www6.paca.inra.fr/umrbcf_eng/) has acquired unique expertise in the domain of lignocellulose-degrading enzymes of fungal origin. Study of the fungal biodiversity is supported by the International Centre for Microbial Resources in Marseille (CIRM-Filamentous Fungi: http://cirm.esil.univ-mrs.fr/). At the genome level, the fungal biodiversity is studied by sequencing fungal genomes and annotating the corresponding gene network.
The contribution to INDOX will be led by Dr Eric Record, Research Director, who has large experience in lignin degrading enzymes (enzyme production, enzymology, and engineering) resulting in ~70 publications (papers, patents and chapters). Other members of the group directly participating in the project are: Prof Craig B. Faulds (deputy director of the INRA UMR), with ~100 publications, will lead WP9 and work on laccase/peroxidase applications; Dr Anthony Levasseur, working on genome annotation with dedicated database (CAZy), enzyme production and characterization; Dr Anne Lomascolo, working on laccase enzymology and applications;Dr Jean-Guy Berrin, working on LPMO production and enzymology;Dr Marie-Noëlle Rosso, working on transcriptome mining;Dr Isabelle Gimbert and Dr Sana Raouche working on enzyme applications; two engineers and one associate engineer (François Piumi, David Navarro, Mireille Haon); andtwo technicians (Annick Doan; Sacha Grisel) working on enzyme production, enzymology and their applications.

Main role in INDOX
The main role of INRA will be the genomic and transcriptomic analyses, with gene mining of heme-peroxidases and gene mining and cloning, characterization of GMC oxidases and laccases, together with research on positive selection within the ORFs to guide directed mutagenesis, enzyme lab-scale production and process development as leader of WP9.
The Institut Technologique FCBA (Forêt Cellulose Bois-Construction Ameublement) is a multi-sector industrial technical institute composed of 340 people working for the whole forest-based and furniture sectors. FCBA has a key role in linking academic research and applied solutions. It participated in various projects aiming at developing wood-based boards industry. FCBA performed extensive work regarding LCA and LCC of fibreboard manufacturing. In collaboration with INRA, FCBA will evaluate the use of oxidoreductases in valorizing industrial lignins for new materials in wood applications (adhesives and preservatives) and to develop original treatment functionalising fibres used in wood-fibres based panels.

Contact person at FCBA: Sandra Tapin-Lingua, Tel: 334.; E-mail: Sandra.TAPIN-LINGUA@fcba.fr

Other people involved: Michaël Lecourt (Michael.LECOURT@fcba.fr); Denilson Da Silva Perez (Denilson.DASILVAPEREZ@fcba.fr); and Jean-Michel Petit-Conil (Michel.PETIT-CONIL@fcba.fr) .
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Project Coordinator
Prof. Angel T. Martínez
Biological Research Centre (CIB, CSIC)
Calle Ramiro de Maeztu 9, E-28040 Madrid, Spain.
E-mail: ATMartinez@cib.csic.es
Phone: 34 918373112
Fax: 34 915360432

Angel T. Martínez is Research Professor of CSIC at the group of Biotechnology for Lignocellulosic Biomass of CIB. He is member of ACS, ASM and TAPPI, with around 250 publications mainly related to oxidoreductases and microbial biotechnology.

His experience is supported by participation in more than 55 national and international research projects, in most of them as head researcher. Regarding EC Framework Programmes, he has coordinated projects of Industrial Biotechnology from FP3 to FP7, such as PEROXICATS (KBBE-2010-4-265397), BIORENEW (NMP2-CT-2006-026456), PELAS (QLK3-1999-00590), PITCH (QLK5-1999-01357) and AIR2 (CT93-1219).
Official webpage of indox [ industrialoxidoreductases ]. Optimized oxidoreductases for medium and large scale industrial biotransformations. This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under Grant Agreement nº: FP7-KBBE-2013-7-613549. © indox 2013. Developed by garcíarincón