Optimized oxidoreductases for medium and large scale industrial biotransformations
Project Secretariat
Dr Marta Pérez-Boada
E-mail: MPBoada@cib.csic.es
Consejo Superior de Investigaciones Científicas (CSIC)
Biological Research Centre (CIB)
Calle Ramiro de Maeztu 9, E-28040 Madrid, Spain
Phone: 34 918373112
Fax: 34 915360432
Mobile: 34 650080476
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about us
tudelftTechnische Universiteit Delft, Delft, The Netherlands (TUDelft)
Contact information
F. Hollmann, Department of Biotechnology, Delft University of Technology, Julianalaan 136, 2628BL Delft, The Netherlands

Phone: +31 15 2781957
E-mail: f.hollmann@tudelft.nl

Description of the group
The “Biocatalysis and Organic Chemistry Group” (www.bt.tudelft.nl/boc) headed by Prof. I.W.C.E. Arends aims at discovery, design and engineering of novel enzymatic pathways leading to target products. To strengthen the focus in the application-oriented research, the understanding of the effect of immobilization (stability as well as compartmentalization) of enzymes is a central research line. The infrastructure of BOC can be described as a combination of base organic chemistry and molecular biology laboratories. In addition, spectroscopy facilities, such as NMR, and EPR are present within the group. For screening of enzymes, a dedicated laboratory is available, that allows performing high-throughput production and assaying of enzymes at advanced safety levels.

Dr. Frank Hollmann will be the scientist in charge o the contribution to INDOX (supported by staff of the Department of Biotechnology). Dr. Hollmann is an internationally renowned expert for the use of enzymes in organic synthesis. His research interests span diverse classes of oxidoreductases for preparative oxidation/reduction and oxyfunctionalization chemistry.Prof. Arends will be also actively involved in the project. In addition Prof. Hanefeld (biocatalysis), Dr. L. Otten (enzyme production), Dr. A Straathof (modeling, reactor design) will be available for consultation.

Main role in INDOX
The group will be active in (and leading) actions in WP7, working on optimization of enzymatic reactions towards industrial application, and will also collaborate in oxyfunctionalization studies and process up-scaling. Hence, TUDelft will act as facilitator between the groups discovering and optimizing new enzymes and the industrial partners wanting to commercialize these enzymes.
->Click on the map locations to access information on the partners

Project Coordinator
Prof. Angel T. Martínez
Biological Research Centre (CIB, CSIC)
Calle Ramiro de Maeztu 9, E-28040 Madrid, Spain.
E-mail: ATMartinez@cib.csic.es
Phone: 34 918373112
Fax: 34 915360432

Angel T. Martínez is Research Professor of CSIC at the group of Biotechnology for Lignocellulosic Biomass of CIB. He is member of ACS, ASM and TAPPI, with around 250 publications mainly related to oxidoreductases and microbial biotechnology.

His experience is supported by participation in more than 55 national and international research projects, in most of them as head researcher. Regarding EC Framework Programmes, he has coordinated projects of Industrial Biotechnology from FP3 to FP7, such as PEROXICATS (KBBE-2010-4-265397), BIORENEW (NMP2-CT-2006-026456), PELAS (QLK3-1999-00590), PITCH (QLK5-1999-01357) and AIR2 (CT93-1219).
Official webpage of indox [ industrialoxidoreductases ]. Optimized oxidoreductases for medium and large scale industrial biotransformations. This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under Grant Agreement nº: FP7-KBBE-2013-7-613549. © indox 2013. Developed by garcíarincón