Optimized oxidoreductases for medium and large scale industrial biotransformations
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Project Secretariat
Dr Marta Pérez-Boada
E-mail: MPBoada@cib.csic.es
Consejo Superior de Investigaciones Científicas (CSIC)
Biological Research Centre (CIB)
Calle Ramiro de Maeztu 9, E-28040 Madrid, Spain
Phone: 34 918373112
Fax: 34 915360432
Mobile: 34 650080476
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publications
Total records: 126
Pages:    1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21  

[ 2014 ] González-Pérez D, Molina-Espeja P, García-Ruiz E, Alcalde M Mutagenic Organized Recombination Process by Homologous In vivo Grouping (MORPHING) for directed enzyme evolution PlosOne, 9: 3
[ 2014 ] Hofrichter M, Ullrich R Oxidations catalyzed by fungal peroxygenases Curr. Opin. Chem. Biol., 19: 116-125
[ 2014 ] Hori C, [...] , Ferreira P, Ruiz-Dueñas FJ, [...] , Rencoret J, Gutiérrez A, [...] , Martínez AT, [...] , Cullen D Analysis of the Phlebiopsis gigantea Genome, Transcriptome and Secretome Provides Insight into Its Pioneer Colonization Strategies of Wood PLOS Genetics, 10: 1004759
[ 2014 ] Isaksen T, Westereng B, Aachmann FL, Agger JW, Kracher D, Kittl R, Ludwig R, Haltrich D, Eijsink VG, Horn SJ A C4-oxidizing lytic polysaccharide monooxygenase cleaving both cellulose and cello-oligosaccharides J. Biol. Chem., 289: 2632-2642
[ 2014 ] Kalum L, Morant MD, Lund H, Jensen J, Lapainaite I, Soerensen NH, Pedersen S, Ostergaard LH, Xu F Enzymatic oxidation of 5-hydroxymethylfurfural and derivatives thereof. WO 2014015256 A2. International Patent Application
[ 2014 ] Kellner H, Luis P, Pecyna MJ, Barbi F, Kapturska D, Krüger D, Zak DR, Marmeisse R, Vandenbol M, Hofrichter M Widespread Occurrence of Expressed Fungal Secretory Peroxidases in Forest Soils PlosOne, 9
year2013
Increasing the Productivity of Peroxidase-Catalyzed Oxyfunctionalization: A Case Study on the Potential of Two-Liquid-Phase Systems
Churakova E, Arends IWCE, Hollmann F
ChemCatChem, 5: 565-568

Biocatalysis, which occurs mostly in aqueous reaction media, is generally incompatible with the hydrophobic nature of many reactants. This may be overcome by using the two-liquid-phase system (2 LPS) approach. We demonstrate the beneficial application of the 2 LPS approach for the photobiocatalytic oxyfunctionalization of thioanisole. Compared to aqueous reaction conditions, the 2 LPS approach not only allowed for higher substrate loadings (without the use of additional solvents) but also increased the productivity and robustness of the overall reaction.

Official webpage of indox [ industrialoxidoreductases ]. Optimized oxidoreductases for medium and large scale industrial biotransformations. This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under Grant Agreement nº: FP7-KBBE-2013-7-613549. © indox 2013. Developed by garcíarincón