Optimized oxidoreductases for medium and large scale industrial biotransformations
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Project Secretariat
Dr Marta Pérez-Boada
E-mail: MPBoada@cib.csic.es
Consejo Superior de Investigaciones Científicas (CSIC)
Biological Research Centre (CIB)
Calle Ramiro de Maeztu 9, E-28040 Madrid, Spain
Phone: 34 918373112
Fax: 34 915360432
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publications
Total records: 126
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[ 2016 ] Maté D, Alcalde M Laccase: a multi-purpose biocatalyst at the forefront of biotechnology Microbial Biotechnol., doi: 10.1111/1751-7915.12422
[ 2016 ] Mathieu Y, Piumi F, Valli R, Carro J, Ferreira P, Faulds CB, Record E Activities of Secreted Aryl Alcohol Quinone Oxidoreductases from Pycnoporus cinnabarinus Provide Insights into Fungal Degradation of Plant Biomass Appl. Environ. Microbiol., 82: 2411-2423
[ 2016 ] Molina-Espeja P, Cañellas M, Plou FJ, Hofrichter M, Lucas F, Guallar V, Alcalde M Synthesis of 1-Naphthol by a Natural Peroxygenase engineered by Directed Evolution ChemBioChem, 17: 341-349
[ 2016 ] Molina-Espeja P, Viña-Gonzalez J, Gomez-Fernandez BJ, Martin-Diaz J, García-Ruiz E, Alcalde M Beyond the outer limits of nature by directed evolution Biotechnol. Adv., 34: 754-767
[ 2016 ] Ni Y, Fernandez-Fueyo E, Gomez Baraibar A, Ullrich R, Hofrichter M, Yanase H, Alcalde M, van Berkel WJ, Hollmann F Peroxygenase-Catalyzed Oxyfunctionalization Reactions Promoted by the Complete Oxidation of Methanol Angew. Chem. Int. Ed., 55: 798-801
[ 2016 ] Olmedo A, Aranda C, del Río JC, Kiebist J, Scheibner K, Martínez AT, Gutiérrez A From Alkanes to Carboxylic Acids: Terminal Oxygenation by a Fungal Peroxygenase Angew. Chem. Int. Ed., 55: 12248-12251
year2015
Specific oxyfunctionalisations catalysed by peroxygenases: opportunities, challenges and solutions
Bormann S, Gomez Baraibar A, Ni Y, Holtmann D, Hollmann F
Catal. Sci. Technol., 5: 2038-2052

Peroxygenases enable H2O2-driven oxyfunctionalisation of organic compounds such as selective epoxidation, hydroxylation and heteroatom oxygenation. Therefore, peroxygenases are potentially very useful tools for the organic chemist. This contribution reviews the current state of the art in peroxygenases, their availability, engineering and reaction scope. Current challenges and possible solutions are critically discussed.

Official webpage of indox [ industrialoxidoreductases ]. Optimized oxidoreductases for medium and large scale industrial biotransformations. This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under Grant Agreement nº: FP7-KBBE-2013-7-613549. © indox 2013. Developed by garcíarincón