Optimized oxidoreductases for medium and large scale industrial biotransformations
Project Secretariat
Dr Marta Pérez-Boada
E-mail: MPBoada@cib.csic.es
Consejo Superior de Investigaciones Científicas (CSIC)
Biological Research Centre (CIB)
Calle Ramiro de Maeztu 9, E-28040 Madrid, Spain
Phone: 34 918373112
Fax: 34 915360432
Mobile: 34 650080476
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about us
cleaCLEA Technologies B.V., Delft, The Netherlands (CLEA)

Roger Sheldon
Contact information
R. A. Sheldon, CLEA Technologies B.V., Delftechpark 34, 2628XH Delft, Netherlands

Phone: 31 157600306
E-mail: r.sheldon@clea.nl

Description of the group
CLEA is a Life Sciences SME based in Delft, Netherlands with broad expertise and experience in the immobilization of enzymes for industrial applications and developing green, biocatalytic processes for the chemical and pharmaceutical industries. The company has key strategic links with the Department of Biotechnology of the Delft University of Technology.

Prof. Roger A. Sheldon, CEO and founder of the company, will lead the contribution to the project. He is the (co)author of seven books, more than 450 scientific publications and more than 50 granted patents. Other members of CLEA Technologies participating in the project are Dr. Paul Konst and Dr. Jo-Anne Rasmussen.

Main role in INDOX
The main role of CLEA will be to immobilize the various enzymes investigated in the project as cross-linked enzyme aggregates (CLEAs). This will increase their thermal stability and tolerance to organic solvents and enable their facile recycling and, hence, cost-effective for industrial applications. Co-immobilization of oxidases and peroxidases will enable their efficient application in cascade processes. CLEA will also contribute to the feasibility studies in the Demonstration activities of the project.
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Project Coordinator
Prof. Angel T. Martínez
Biological Research Centre (CIB, CSIC)
Calle Ramiro de Maeztu 9, E-28040 Madrid, Spain.
E-mail: ATMartinez@cib.csic.es
Phone: 34 918373112
Fax: 34 915360432

Angel T. Martínez is Research Professor of CSIC at the group of Biotechnology for Lignocellulosic Biomass of CIB. He is member of ACS, ASM and TAPPI, with around 250 publications mainly related to oxidoreductases and microbial biotechnology.

His experience is supported by participation in more than 55 national and international research projects, in most of them as head researcher. Regarding EC Framework Programmes, he has coordinated projects of Industrial Biotechnology from FP3 to FP7, such as PEROXICATS (KBBE-2010-4-265397), BIORENEW (NMP2-CT-2006-026456), PELAS (QLK3-1999-00590), PITCH (QLK5-1999-01357) and AIR2 (CT93-1219).
Official webpage of indox [ industrialoxidoreductases ]. Optimized oxidoreductases for medium and large scale industrial biotransformations. This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under Grant Agreement nº: FP7-KBBE-2013-7-613549. © indox 2013. Developed by garcíarincón