Optimized oxidoreductases for medium and large scale industrial biotransformations
Project Secretariat
Dr Marta Pérez-Boada
E-mail: MPBoada@cib.csic.esConsejo Superior de Investigaciones Científicas (CSIC)
Biological Research Centre (CIB)
Calle Ramiro de Maeztu 9, E-28040 Madrid, Spain
Phone: 34 918373112
Fax: 34 915360432
Mobile: 34 650080476
Private area
publications
Pages:
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[ 2016 ]
Ewing TA, Gygli G, van Berkel WJ A single loop is essential for the octamerisation of vanillyl alcohol oxidase
FEBS J., doi: 10.1111/febs.13762
[ 2016 ]
Fernandez-Fueyo E, Ni Y, Gomez Baraibar A, Alcalde M, van Langen LM, Hollmann F Towards preparative peroxygenase-catalyzed oxyfunctionalization reactions in organic media
J. Mol. Cat. B, doi: 10.1016/j.molcatb.2016.09.013
[ 2016 ]
Fernandez-Fueyo E, Ruiz-Dueñas FJ, López-Lucendo MF, Pérez-Boada M, Rencoret J, Gutiérrez A, Pisabarro AG, Ramírez L, Martínez AT A secretomic view of woody and nonwoody lignocellulose degradation by Pleurotus ostreatus
Biotechnol. Biofuels, 9: 49
[ 2016 ]
Fernandez-Fueyo E, Younes SHH, van Rootselaar S, Aben RWM, Renirie R, Wever R, Holtmann D, Rutjes FPJT, Hollmann F A Biocatalytic Aza-Achmatowicz Reaction
ACS-Catalysis, 6: 5904-5907
[ 2016 ]
Garajova S, Mathieu Y, Beccia MR, Bennati-Granier C, Biaso F, Fanuel M, Ropartz D, Guigliarelli B, Record E, Rogniaux H, Henrissat B, Berrin JG Single-domain flavoenzymes trigger lytic polysaccharide monooxygenases for oxidative degradation of cellulose
Sci. Rep., 6: 28276
[ 2016 ]
González-Pérez D, Mateljak I, García-Ruiz E, Ruiz-Dueñas FJ, Martínez AT, Alcalde M Alkaline versatile peroxidase by directed evolution
Catal. Sci. Technol., 6: 6625-6636
year2016
Towards preparative peroxygenase-catalyzed oxyfunctionalization reactions in organic media
Fernandez-Fueyo E, Ni Y, Gomez Baraibar A, Alcalde M, van Langen LM, Hollmann F
J. Mol. Cat. B, doi: 10.1016/j.molcatb.2016.09.013
The peroxygenase from Agrocybe aegerita (AaeUPO) has been evaluated for stereoselective oxyfunctionalization chemistry under non-aqueous reaction conditions.
The stereoselective hydroxylation of ethylbenzene to (R)-1-phenylethanol was performed in neat substrate as reaction medium together with the immobilized biocatalyst and tertBuOOH as oxidant.
Stability and activity issues still have to be addressed. Nevertheless, gram-scale production of enantiopure (R)-1-phenylethanol was achieved with respectable 90,000 turnovers of the biocatalyst.
Official webpage of 
[ industrialoxidoreductases ]. Optimized oxidoreductases for medium and large scale industrial biotransformations. This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under Grant Agreement nº: FP7-KBBE-2013-7-613549. © indox 2013. Developed by garcíarincón
[ industrialoxidoreductases ]. Optimized oxidoreductases for medium and large scale industrial biotransformations. This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under Grant Agreement nº: FP7-KBBE-2013-7-613549. © indox 2013. Developed by garcíarincón